Treatise


Dr. In-Hu Hwang CEO / Founder of IH bio Inc.- Treatise -


Dr. 황 인후 CEO / Founder of IH bio Inc.논문자료

1. Modified Ginseng Extract Induces Apoptosis in HepG2 Cancer Cells by Blocking the CXCL8-Mediated Akt/Nuclear Factor-[Formula: see text]B Signaling Pathway. Cui, Z. Y., Jo, E., Jang, H. J., Hwang, I. H., Lee, K. B., Yoo, H. S., ... & Jang, I. S. (2018). Modified Ginseng Extract Induces Apoptosis in HepG2 Cancer Cells by Blocking the CXCL8-Mediated Akt/Nuclear Factor-κ B Signaling Pathway. The American journal of Chinese medicine, 46(07), 1645-1662. https://www.ncbi.nlm.nih.gov/pubmed/30284465 2. Allergen-Removed Rhus verniciflua Extract Induces Ovarian Cancer Cell Death via JNK Activation. Kang, S. H., Hwang, I. H., Son, E., Cho, C. K., Choi, J. S., Park, S. J., ... & Yoo, H. S. (2016). Allergen-removed Rhus verniciflua extract induces ovarian cancer cell death via JNK activation. The American journal of Chinese medicine, 44(08), 1719-1735. https://www.worldscientific.com/doi/abs/10.1142/S0192415X16500968 3. Houttuynia cordata Thunb Promotes Activation of HIF-1A-FOXO3 and MEF2A Pathways to Induce Apoptosis in Human HepG2 Hepatocellular Carcinoma Cells. Kim, J. M., Hwang, I. H., Jang, I. S., Kim, M., Bang, I. S., Park, S. J., ... & Lee, M. G. (2017). Houttuynia cordata Thunb promotes activation of HIF-1A–FOXO3 and MEF2A pathways to induce apoptosis in human HepG2 hepatocellular carcinoma cells. Integrative cancer therapies, 16(3), 360-372. https://www.ncbi.nlm.nih.gov/pubmed/27698266 4. Modified Panax ginseng Extract Inhibits uPAR-Mediated α[Formula: see text]β1-Integrin Signaling by Modulating Caveolin-1 to Induce Early Apoptosis in Lung Cancer Cells. Hwang, I. H., Kwon, Y. K., Cho, C. K., Lee, Y. W., Sung, J. S., Joo, J. C., ... & Jang, I. S. (2016). Modified Panax ginseng extract inhibits uPAR-mediated α 5 β1-integrin signaling by modulating caveolin-1 to induce early apoptosis in lung cancer cells. The American journal of Chinese medicine, 44(05), 1081-1097. https://www.ncbi.nlm.nih.gov/pubmed/27430913 5. Phenyl 2-pyridyl ketoxime induces cellular senescence-like alterations via nitric oxide production in human diploid fibroblasts. Yang, K. E., Jang, H. J., Hwang, I. H., Chung, Y. H., Choi, J. S., Lee, T. H., ... & Jang, I. S. (2016). Phenyl 2‐pyridyl ketoxime induces cellular senescence‐like alterations via nitric oxide production in human diploid fibroblasts. Aging cell, 15(2), 245-255. https://www.ncbi.nlm.nih.gov/pubmed/26696133 6. Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling. Kyeong-Eun Yang Hyun-Jin Jang In-Hu Hwang Eun Mi Hong Min-Goo LeeSoon Lee Ik-Soon Jang Jong-Soon Choi. Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling. Journal of Ginseng Research Available online 13 August 2019 https://www.sciencedirect.com/science/article/pii/S122684531930034X 7. Nectandrin B-mediated activation of the AMPK pathway prevents cellular senescence in human diploid fibroblasts by reducing intracellular ROS levels. Aging (Albany NY). 2019 Jun 14;11(11):3731-3749Hyun-Jin Jang1, Kyeong Eun Yang, Won Keun Oh, Song-I Lee, In-Hu Hwang, Kyung-Tae Ban, Hwa-Seung Yoo, Jong-Soon Choi, Eui-Ju Yeo4, Ik-Soon Jang. Nectandrin B-mediated activation of the AMPK pathway prevents cellular senescence in human diploid fibroblasts by reducing intracellular ROS levels. Aging (Albany NY). 2019 Jun 14;11(11):3731-3749 https://www.ncbi.nlm.nih.gov/pubmed/31199782 8. Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway. Cui, Z. Y., Park, S. J., Jo, E., Hwang, I. H., Lee, K. B., Kim, S. W., ... & Jang, I. S. (2018). Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway. Cell death discovery, 4(1), 62. https://www.nature.com/articles/s41420-018-0063-4 9. Modified Ginseng Extract Induces Apoptosis in HepG2 Cancer Cells by Blocking the CXCL8-Mediated Akt/Nuclear Factor-[Formula: see text]B Signaling Pathway. Cui, Z. Y., Jo, E., Jang, H. J., Hwang, I. H., Lee, K. B., Yoo, H. S., ... & Jang, I. S. (2018). Modified Ginseng Extract Induces Apoptosis in HepG2 Cancer Cells by Blocking the CXCL8-Mediated Akt/Nuclear Factor-κ B Signaling Pathway. The American journal of Chinese medicine, 46(07), 1645-1662. https://www.ncbi.nlm.nih.gov/pubmed/30284465 10. Proteomic analyses reveal that ginsenoside Rg3(S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin. Jang, I. S., Jo, E., Park, S. J., Hwang, I. H., Kang, H. M., Lee, J. H., ... & Choi, J. S. (2018). Proteomic analyses reveal that ginsenoside Rg3 (S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin. Journal of Ginseng Research. https://www.sciencedirect.com/science/article/pii/S1226845317303937 11. Tetraspanin-2 promotes glucotoxic apoptosis by regulating the JNK/β-catenin signaling pathway in human pancreatic β cells. Hwang, I. H., Park, J., Kim, J. M., Kim, S. I., Choi, J. S., Lee, K. B., ... & Jang, I. S. (2016). Tetraspanin-2 promotes glucotoxic apoptosis by regulating the JNK/β-catenin signaling pathway in human pancreatic β cells. The FASEB Journal, 30(9), 3107-3116.


About Dr. In-Hu Hwang CEO / Founder of IH bio Inc. ●  리더쉽       ●   leadership

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